题目：Exploring the functional brain through connectivity:  how and why

主讲人：Dr.Xavier Noguès,

Centre for Integrative and Cognitive

Neuroscience, University of Bordeaux, France

时间：10月28日（周四）上午10:00—11:20

地点：小楼三层会议室

邀请人：贺永

由实验室贺永老师邀请了Centre for Integrative and CognitiveNeuroscience,  University of Bordeaux, France的Dr.Xavier Noguès来实验室做报告，具体信息如下，欢迎感兴趣的老师参加。谢谢！

报告摘要：

How bran makes cognition ? How can the brain be so adaptable ? We will  hypothesize that the formation of specific functional networks generates  specific cognitive processes. Accordingly, a suited approach may consist, not  only in identifying the structures involved in a task, but also in describing  how they are connected.

In order to explore this concept, mice are trained in two tasks involving two  basic cognitive processes. A first step will consist in verifying that the two  tasks promote two different patterns of functional connectivity whithin the same  set of structures. The second step consists in describing the effective  connectivity network. In this goal, we have evaluated the validity and  reliability of structural equation modeling (SEM method). The results led us  to propose a statistical test dedicated to compare effective connectivity  networks obtained by SEM under various experimental conditions. preliminary  results using this test will be presented.

If this concept of brain functioning is somewhat true, we hope that it will  trigger a new approach for therapies, both at pharmacological and  neuropsychological levels

报告人简介

Xavier Noguès, male, cognitive neuroscientist, graduated from psychology  department, Bordeaux University (France). He conducted his European Doctorate in  Cognitive Neurosciences in the Department of Biology, Bordeaux University, in  collaboration with the Department of Pharmacology, Milan University (Italia) and  with the Department of Physiology, Gröningen University (the Netherlands). These  studies bore on the involvement of protein kinases in memory. After his PhD  thesis, he worked as assistant professor during one year (Department of  Psychology) on Human spatial mapping in virtual environments, and then as  associate professor in cognitive neuroscience. His research now focuses on the  involvement of brain connectivity in cognitive processes and pathologies. The  aim of his most recent studies is to develop new reliable methods suited to the  study of connectivity.