各位老师：

您好！实验室邀请了Stanford University的Shaozheng Qin博士来实验室做报告，欢迎感兴趣的老师来听！报告时间：9月16日（下周一）上午10点

报告地点：脑成像中心308会议室（大会议室）

报告题目： Brain functional reorganization  underlies cognitive and affective development in humans

报告摘要：From childhood to adulthood, the  development of large-scale brain functional networks underlies the maturation of  increasingly nuanced cognitive and affective abilities. Yet, our understanding  of how the brain development contributes to maturation of human cognitive and  affective abilities is still in its infancy. Using multi-disciplinary approach  integrating state-of-the-art cognitive neuroimaging, psychophysiology and  genetics, Dr. Qin's research is to understand the neurocognitive basis of  learning and memory and interaction with emotion and stress, and the development  of emotion and memory systems from childhood to adulthood. First, findings from  a series of his recent studies suggest that the hippocampus and the amygdala  plays a central role in mediating learning and memory and interaction with  emotion and stress, through their complex interplay with distributed brain  regions important for attention, perception and executive functions. Second,  when compared to adolescents and adults, children show significantly weaker  integration and weaker segregation among functional networks of emotion- and  memory-related brain circuitry. Critically, levels of childhood anxiety can  greatly affect emotion-related circuitry in the developing brain. Third,  integrating with longitudinal and cross-sectional fMRI studies, Dr. Qin’s  research further demonstrate that the hippocampal-neocortical reorganization is  pivotal to strategic shifts from procedural to memory-based problem solving – a  cardinal feature for children’s cognitive development. Specifically, maturation  of memory-based problem solving is associated with increased hippocampal  engagement during childhood, and increased functional coupling between the  hippocampus and frontoparietal cortices. This hippocampal dependence, however,  decreases significantly from middle childhood through adolescence into  adulthood. Altogether, converging findings from above three-pronged lines of  research point toward that brain functional reorganization underlies  increasingly nuanced cognitive and affective abilities over development.  Potential implications for future research in cognitive neuroscience and brain  development will be discussed.

报告人简介

Dr. Shaozheng Qin received his Ph.D.  in cognitive neuroscience from Donders Institute for Brain, Cognition and  Behavior in November of 2010. He currently works as a research fellowship at  Stanford University. His primary research of interest is to understand the  neuro-cognitive basis of learning and memory and interaction with emotion and  stress, and the neurodevelopment of emotion and memory systems from childhood  through adolescence into adulthood. The overarching inspiration is to optimize  learning and memory in education and to develop intervention programs for  preventing learning disabilities, memory impairments and emotional problems in  early development in children.Using a multi-disciplinary approach  integrating cognitive neuroimaging, psychophysiology and genetics, my research  consists of three specific inter-related questions: How the brain, particularly  the medial temporal lobe and prefrontal cortex – two core memory neural systems,  supports learning and memory? How these core memory systems are modulated by  emotion? How these systems mature over development from childhood through  adolescence into adulthood? His works have been published on high profile  journals, such as Science, PNAS, Biological Psychiatry, Journal of Neuroscience  and Neuroimage.

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敬礼！

认知神经科学与学习国家重点实验室

2013年9月10日