各位老师：

您好！由李武老师邀请了Rockefeller  University的Charles D. Gilbert  教授（美国科学院院士）来实验室做讲座，欢迎感兴趣的老师和同学参加。讲座信息如下：

讲座时间：7月26日（本周五）上午9:30

讲座地点：脑成像中心308会议室（大会议室）

主讲人：Charles D. Gilbert  教授，美国科学院院士

讲座题目：Adult cortical  plasticity and perceptual learning

内容摘要：All cortical levels of  sensory processing are capable of undergoing long term experience dependent  functional changes, resulting from the normal process of perceptual learning and  from functional recovery following CNS lesions. The circuitry underlying these  changes includes the plexus of long range horizontal connections formed by  cortical pyramidal cells and the axons of inhibitory interneurons. Alteration of  sensory experience leads to a rapid and massive modification of these  connections, involving exuberant outgrowth of new axon collaterals and a  parallel process of pruning of existing and newly grown axon collaterals. The  signal transduction pathways mediating these changes involve neurotrophin  expression and a pathway that mediates apoptosis during development, but is  recruited for modification of axonal arbors in the adult in the absence of cell  death. Though sensory experience involves synaptogenesis and synaptic  elimination, its mechanism must also account for input selection, where neurons  express functional properties associated with a learned task only when the task  is being executed. Long term modification and short term gating of cortical  circuits therefore underlies the experience and task dependent dynamics of  cortical function.

主讲人介绍：

Charles D. Gilbert is  the Arthur and Janet Ross professor at The Rockefeller University, New York,  USA. He is a member of the National Academy of Sciences and the American Academy  of Arts and Sciences. His work focuses on the brain mechanisms of visual  perception and learning at the molecular, circuit and perceptual levels. He  studies the way in which the brain analyses visual images, how this analysis is  shaped by higher-order cognitive influences and by perceptual learning and the  circuit mechanisms of experience-dependent plasticity of the adult visual  cortex.

    此致

敬礼！

认知神经科学与学习国家重点实验室

2013年7月22日